Naltrexone did not work with PLMD

Naltrexone worked for my RLS but did not work for my PLMD - I have the Apple Watch data to prove it. I was comfortable but my sleep quality was terrible, dozens of awakenings all night long. If anything, I think it made it worse. It makes zero sense. Other opiates work for both, but with unbearable side effects. Has anyone else had this experience? Looking for ideas on why this might be.