How long does sertraline fatigue last?

Medication

I just started it at 25mg and I’m feeling tired and out of it. Not very functional. I’m supposed to ramp up to 50mg in the next week or so, but I’m not sure if I can manage when I’m already this tired and foggy and have to function at work and with my kids. Anyone who has taken it, what’s been your experience on it with side effects? How long did they last?

Posted Feb 15, 2026, 3:02 AM UTC

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