Has anyone switched from Tirazepitide to Ozempic because they couldn’t tolerate the Tirazepitide? How did it go for you?
I tried Zepbound a year ago and it made me SO sick. It was fine for about a week and a half, and actually I felt really good. My pain and inflammation decreased significantly. But then on day 11 I woke up with a bit of stomach pain, and then started vomiting and couldn’t stop. I ended up in the ER and getting admitted for three days because I was so dehydrated and couldn’t keep anything down.
I’m curious if anyone here had a similar experience with Zep and was able to successfully switch to Ozempic and not have that same reaction? I want to try it, I wish so badly that I could’ve tolerated the Zepbound, the impact it had on my inflammation and joint pain was incredible.
Posted Feb 17, 2026, 3:17 AM UTC
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