Pristiq cross tapered to lexapro, any advice will be helpful

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Hi all

In October 2025 I tried tapering clonazepam from .5 to .325 while on pristiq 50 , I drank alcohol for a week during the birthday week , I developed dpdr anxious thoughts next I went to doctor , she increased my pristiq to 75 which caused significant restlessness, I went to doctor again in a week she decided she will cross tapered me to escitalopram which I tolerated very well for few years earlier , which she did very fast, my last dose of pristiq 25 which I took only for 1 week was on 19 Dec, since end of December I am getting afternoon adrenaline like waves and I cry out and feel normal by evening, I am on 1 mg clonazepam and 15 mg lexapro and recently added lithium for my crying spells, recently since a week I am getting crying spells in morning also, the afternoon waves intensity reduced, but I am very scared if I am loosing my window of reinstatement of pristiq 25, any advice will be helpful

Posted Feb 20, 2026, 4:30 PM UTC

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