Stage III rectal (pCR, ctDNA negative) – 5mm lung nodule on follow-up CT
Hi everyone,
I would really appreciate hearing your experiences.
Has anyone had small lung nodules detected on CT after completing treatment, and later found that they stayed stable or disappeared?
My case:
Rectal cancer, stage III (T3a/b, initially N+, no EMVI)
Chemoradiation → CAPOX x2 → surgery (pathology: pCR, no residual cancer found)
Adjuvant CAPOX x4
ctDNA negative twice
Three months after finishing treatment, CT showed a 5 mm nodule and two smaller ones.
All three of my doctors (surgeon, radiation oncologist, and medical oncologist) are not concerned and scheduled a follow-up CT in 6 months, saying it is likely not something worrisome.
Still, I can’t help but feel anxious.
If you’ve had a similar experience, what size were your nodules and what was the outcome?
Thank you so much
Posted Feb 25, 2026, 5:48 AM UTC