Interesting study (Jan.2026) in Endocrine connection
https://pmc.ncbi.nlm.nih.gov/articles/PMC12811712/
Conclusion:
"Physiological dose tapering in glucocorticoid-induced adrenal insufficiency enables, rather than follows, hypothalamic–pituitary–adrenal axis recovery, with structured, symptom-led tapering being safe and effective. Future guidelines should recognise that the HPA axis is suppressed by physiological doses."
They suggest that slow tapering, even in those with low am cortisol, can spur on recovery in those with reversible forms of AI.
Posted Feb 25, 2026, 9:04 PM UTC
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