Zoloft vs. Prozac

SUPPORT REQUEST

Not medical advice just opinions!

I have symptoms of anxiety, panic, OCD and depression. And ADHD.

I have taken Zoloft 2-3 times in the past and within 1-2 weeks I feel so much better with all my symptoms but I am 100% more tired all day, even if I take it at night.

I have taken Wellbutrin twice and it’s not for me.

I started Prozac about 4-5 weeks ago, 2 on 10 and past 2-3 weeks on 20.

It has helped keep my panic calm, the anxiety was super bad but seems to be leveled out but still anxious. I still feel depressed. But my energy is way better.

Does anybody have any experience or opinions on what I should do, any medications to add to help? I’ve seen Prozac with Buspar or Zoloft with ADHD meds (but my dr wants me to “get my mood under control” before trying ADHD meds).

My doctor suggests things but of course the ball is kind of in my court to let the doctor know what’s working or not working.

She said to try 20mg for a month and see how I feel.

I just feel like the ADHD is out of control and the OCD and that is causing me depression. I feel like I need to get the anxiety under control first before the depression not the other way.

I loved the Zoloft but I still got nothing done during the day because I was just so exhausted and drinking so much coffee. Prior to taking the Prozac I was more tired than I’ve ever been in my life so I can’t image adding Zoloft to that.

I

Posted Feb 26, 2026, 3:27 AM UTC

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