How are you supposed to get experience if no one hires without experience?

I’m honestly starting to feel stuck and would really appreciate some perspective from people already in clinical research. For the past year, I’ve been trying to transition from biotech into clinical research. I apply pretty much daily, and I tailor my CV and cover letter for every single role, reached out to recruiters on LinkedIn (mostly entry-level positions, like CTA, junior CRA, data management roles). And yet, almost every rejection comes down to the same feedback that they are looking for candidates with prior experience in a CRO, even for entry level roles.

What I genuinely don’t understand is how is anyone supposed to get this experience if no one seems willing to hire “juniors” and recently graduates?

I’m not coming from an unrelated background either, I come from a biotech/research background. At this point I’m trying to figure out whether I’m missing something strategically, or if this is just a timing issue with the industry. Any advice would be really appreciated.