Low mood, anxiety, disappearing libido

Side Effects

I’m 6 weeks into my Mounjaro journey. The main symptom I had on 2.5mg was insomnia/agitation but it was settling down and food noise was back as I approached the 4 week mark. So I moved up to 5mg. I feel dreadful. Low mood, insomnia, vivid dreams, anxiety, generally feeling like I want to shut out the world and hide away. I’m also completely wiped out and feeling weak, despite eating. Is this normal? I’m struggling to function at work.

Additionally - and most disturbingly - my libido has vanished with my appetite for food. I feel dead and unenthusiastic about life, which is not at all like me. I’m generally a happy soul. I’ve lost 4kg so far so it’s not a result of rapid weight loss. I’m due to jab again on Sunday but I don’t think I can bear to. Has anyone else had this experience? 😔

Posted Mar 4, 2026, 7:11 AM UTC

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