Restarting Zoloft- anyone relate?

Question

Hello all- 32 F

About 2.5 weeks postpartum with my second baby. Overall anxiety has been getting a bit intense this time so I decided to go back on Zoloft. I haven’t been on medication in about 3 years other than as needed to panic attacks or more extreme days which luckily has been far and few between due to therapy, diet and exercise.

This will be my fourth time on Zoloft and I was very apprehensive about taking it again as my symptoms starting it are usually severe. The last few times taking it I’m usually put on about 75 mg and sometimes go up but I’ve never started as low as I am now at 25 mg. Just curious to see if anyone restarting especially at such a low dose experienced major symptoms?

My symptoms usually include

-increased anxiety

-insomnia

-diarrhea

-lack of appetite

-nausea

-Ruminating thoughts

-agitation

-restlessness

-brain fog

The lucky thing is that each time I’ve taken this typically the first 3ish days are really hard and they slowly start to get better and by a week I feel much better- not sure if Zoloft is working by then or if the symptoms dissipating are just such a relief. But I do typically notice I’m not ruminating by the end of the week and my sleep has greatly improved. But I’m mainly taking this because I’m breast feeding and I know it’s workedfor me in the past. Just curious if anyone has had these symptoms especially at a low dose or starting again after so long changed anything for you?

Thank you!

Posted Mar 4, 2026, 11:55 AM UTC

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