Observations on Reta and electrolyte depletion in research subjects? 🧪💧

During recent research cycles with Retatrutide, I've noticed the subject requires a significantly higher intake of electrolytes compared to previous GLP-1 or GIP-only protocols.

Hypothetically, since Reta targets the glucagon receptor, it seems to accelerate the flushing of fluids and minerals. I've had to double the sodium and potassium titration just to maintain baseline stability in the research environment.

Has anyone else adjusted their hydration protocols specifically for Reta's triple-agonist profile? Looking for science-based feedback on managing this effectively. 🐀