Low dose gaba and breakthrough episodes

Hey, y'all.

My cat got diagnosed in December after a flea infestation and a stressful event right afterwards (we moved). She's been on 25mg gabapentin twice a day since then which has been sufficient until about four days ago. She's had three mini episodes since - no mutilation, no biting, just severe twitching for a few seconds which can be abated by just pressing lightly on her back (this has always been the case with her). I'm guessing bumping her to 50mg would help, but I know from this sub that eventually something else needs to be added.

Here's the issue: I have ZERO idea what the trigger is. Her first FHS episode was when she was seven months old (she's two now) when my neighbors were having a party she didn't like (same, girl). She just had a brief episode after my husband failed to return her "woo" sound in the hallway because he fell asleep. I assume her main issue is anxiety since she was feral when I got her and she didn't get handled a lot as a baby and small anxiety events set her off, but it also seems worse when it's super dry in the house.

For people who have introduced an anti-anxiety med like fluoxetine, have you noticed any breakthrough events? Also, how concerned should I be about super mild breakthroughs? It's going to be at least two weeks until our next follow up and I just want some input from other people.

Posted Mar 6, 2026, 4:13 AM UTC

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