Symptoms for valacyclovir: you got to be kidding me

Had a really bad outbreak this week and was prescribed valacyclovir for it. I take acyclovir daily for prevention normally but haven’t since I started valacyclovir.

At this point, I’d rather have had the outbreak unmediated. These drugs have made me feel much worse.

Here’s everything I’ve experienced being on them:

Cold/flu symptoms: headaches, body aches, swollen lymph nodes, sneezing, sore throat

Digestion: diarrhea, loud and unsettled stomach, nausea, car/motion sickness

Other: depression, anxiety, insomnia, vivid dreams, tiredness, feeling stoned, and brain fog

This is really the best we got? Are you serious? Does no one care about us? A drug with this many side affects just to treat some itchy bumps and body aches SHOULD NOT BE THIS BAD.

Pros do not outweigh the cons here

Posted Mar 6, 2026, 3:40 PM UTC

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