r/POFlife•
ToadCroaks

Am I the only one who can't tolerate bio-Progesterone?

Hi ladies,

Wanted to know how many or us there are who can't tolerate bio identical progesterone specifically!

I'm not talking about synthetic like Mirena here but about Utrogestan, Prometrium and micronized Progesterone.

Here's the symptoms bio identical progesterone causes for me:

  • weight gain
  • edema
  • muscle loss
  • joint pain
  • vision problems
  • dull skin
  • back pimples
  • anger / aggression
  • high hunger
  • worsened hot flashes and night sweats
  • ear itching
  • poor wound healing
  • insomnia

Anyone else dealing with this?

Posted Mar 6, 2026, 8:51 PM UTC

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