Has anyone else had a sudden spike in TSH?

22F, had TT 2.5 years ago (Aug 2023). I’ve been on 112 mcg levo for most of this time, in late 2024 my TSH suddenly started going up, peaking at 3.5. Endo increased my levo all the way to 137 by Jan 2025 and I felt way too hyperthyroid to continue with that dose and asked him if anything else could possibly be going on. He threw out a gluten-free diet as a possibility and tested me for celiac in April and I surprisingly came back positive (I only had subtle symptoms of celiac and blamed it on other things). Going GF worked for a time, and I was back down to the 0.1-0.5 TSH range and 112 mcg by September.

But on Monday I got a routine TSH test and it was 10.7! Nothing has changed with how I take levo: always at least an hour before food and 4 hours before things like calcium and magnesium, still eating GF. Endo ordered a retest on Friday and it was down to 6.9 which is still higher than it’s ever been but makes me think something happened to cause a brief spike. I was in the ER a month ago for an asthma attack and wonder if maybe something they gave me there did it? All I can find online is things that raise TSH in people with thyroids, so I figured this community might have better insight. TIA

Posted Mar 8, 2026, 5:59 PM UTC

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