Did your psych tell you to alternate between/take breaks from stimulant meds to avoid developing resistance?
I’d like some input on how this works and if it works at all.
If you do alternate, how do you know when to switch meds? How long have you been alternating? Has it been going well for you? Can you still focus no matter what med you take?
Or do you take breaks instead? How long are your breaks? How do you feel on your off days?
Backstory if you’re interested: I just started Adderall ER today because I developed a resistance to Modifinil (different kind of stimulant) after taking it daily for a year. The past 6 months have been hell with it barely doing more than a cup of coffee and being gone by lunchtime. Adderall works better, 1000%, my mind is quieter, I’m not falling asleep at my desk, and I can focus so much more. I’d prefer to take it every day if I could because there’s *always* work to do. But my psych directed me to go off of it every now and then and resume taking Modifinil.
I’ll be honest, I’m not confident about this plan, but I don’t want to gain a resistance to amphetamines too. Could use some input on how this works and if it works at all.
(If you’re wondering why Modifinil came first, it’s because convincing psychiatrists to treat ADHD when you don’t have an “official” diagnosis is impossible. Getting a psych to treat “excessive daytime sleepiness” as a symptom of sleep apnea, which I am diagnosed with, is easier.)
Posted Mar 8, 2026, 8:01 PM UTC