Cat bites my wife but not me

So our cat is a beauty and a total shit who we live desperately. She's naughty and knows it but generally is actually a great cat who loves being carried, petted, tummy rubs etc. She, annoyingly however attacks my wife with bites with real vigor and regularly draws blood. Hands and feet. It sucks because she is clearly more comfortable with my wife overall and she's really unhappy with the situation. Any ideas?