Bad anxiety with HRT??

For context I have been on hormones (2mg oral estriadiol and 50mg Spironolactone) since Late November. Lately the past month or so my anxiety has been terrible. I've had anxiety my whole life but it has been debilitating so much so I am on medical leave from work until April. Granted I am a night shift nurse and work a stressful job, but I have been doing this for a year and a half and never had panic like I do right now. I am wondering if anyone else has noticed increased anxiety from HRT? I love the changes from HRT and I don't wanna stop but am contemplating it because I can't function at work like this. I am now on Prozac and have Xanax but I am just scared... Is my body rejecting the hormones? Everyones mental health seems to get so much better on HRT so why is mine declining : ( Would switching doses help? I am waiting for labs but my T last month was really high still. Just need someone to talk to