What to do with DEPLORABLES?

Say theoretically that 15% of America consists of genetic deplorables. In other words, they are genetically predisposed to act in a way that the other 85% find truly abhorrent. (They tend to selfish, steal, grape, murder, etc.) These 15% can consist of our brothers, our mothers, and our friends.

First, is the majority abusing their power against a minority in this situation?

Second, if it is decided that certain traits are truly worthy to be eradicated, what is the ideal solution to deal with deplorables?

For example, should society cast them out? Neuter them?

What would be the optimal solution?