Opinions on delaying second jab?

I started Mounjaro (2.5) on Thursday last week. I found my side-effects to be manageable (some burping and feeling a bit nauseous), but my appetite suppression was really quite strong. My mindset for the past week has been "how do I eat enough?", which is obviously a refreshing change which I'm really grateful for, but I do want to lose weight healthily and not too quickly. For reference, I had lost 1.9kg on Thursday morning (one week in), and I'm short, so that's quite a lot for me.

It's now Friday, i.e. day 8, I haven't done my second jab yet and my suppression is still strong. I know the mounjaro builds up in your system, and I'm a bit worried if I jab again now, the suppression will be too much and I'll really struggle to eat.

Should I delay my injection until I feel some hunger/Day 10 or so? Is this a situation where I need to trust the process, or my body? Again, I'm really pleased with how the first week has gone; I just don't want to go too fast.

(I have reached out to my provider to ask this q, but I think they're not monitoring over Easter weekend).

Posted Apr 3, 2026, 4:45 PM UTC

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