Paradoxical reactions from thiamine mononitrate or B1 infusions? Prevention?

Supplements

My thiamine was really low and has stabilized a little to be closer to normal range but I still react badly when I do thiamine infusions or take thiamine mononitrate.

I seem to get paradoxical reactions from thiamine (vitamin B1). I experience fatigue. rampant anxiety especially when driving or workout out.I’m also taking magnesium with it.

Has anyone else had this happen from B1? What did you take or do that help fix it or prevent the paradoxical reaction?

Mostly looking to hear what actually helped people tolerate thiamine better.

Posted Apr 5, 2026, 2:51 AM UTC

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