Pristiq only helps with my anxiety, not depression

Hi all,

I started Pristiq for both depression and anxiety around 2 months ago. I also have OCD that mainly shows up in the form of hypochondria. I've noticed my obsessive thoughts and physical symptoms of anxiety have severely lessened. I used to think I was dying every day, and I recently realized I haven't had those debilitating thoughts in a minute. However, my depression hasn't improved. If anything it's much worse, but that could maybe be situational. I can't get myself to do anything. Has anyone else had this experience? I love the Pristiq for my anxiety, but I need to do something about the depression problem ASAP. Has anyone tried Pristiq with Wellbutrin?

Posted Apr 9, 2026, 7:51 PM UTC

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