4 years IBS and nothing helps

Hey everyone,

I’m honestly at a point where I really need help or at least to know if someone has experienced something similar.

I’ve had IBS for about 4 years now. In the beginning it was mostly frequent (3-4 times a week) bloating and cramping, but over time it has gotten worse.

Now my main symptoms are:

– severe daily bloating (i don‘t have a huge bloated belly, but can feel the gas and tension inside)

– a LOT of gas (often trapped)

– constipation / incomplete evacuation

– I can poop every day (even multiple times), but never feel fully empty

– I sometimes sit on the toilet for 30–40 minutes because it comes in waves (gas + stool)

My mornings are really bad and take so much time:

I wake up and immediately have to go to the bathroom (not urgent/ not diarrhea but a lot of gas and then stool), then again maybe an hour later, and again after breakfast.

Then it’s usually fine for a couple of hours and by the afternoon/evening I get really bad bloating & gas.

When I am not home or going out and can‘t relax, symptoms are worse because I get very tense. Then gas is trapped even more.

I’ve done pretty much every test:

– colonoscopy & gastroscopy

– SIBO breath tests (lactulose & glucose)

– lactose, fructose, sorbitol intolerance tests

– H. pylori

– microbiome test

– stool test + parasites

– HPU test

Everything is basically “normal” or inconclusive. (Just had some dysbiosis, h. pylori, low DAO and mild inactive chronic gastritis but not getting better after treating it).

The weird thing is:

My symptoms fit IMO (methane SIBO) a lot, but my breath tests were negative (methane didn’t rise more than 10 ppm).

But I noticed that my baseline values were already kind of elevated in multiple tests, which I find strange. Did anyone have false negative SIBO tests (i did 3 in total)?

I also have:

– endometriosis + adenomyosis

– probably adhesions (I had a ruptured appendix when I was 10)

Right now I’m planning to do anorectal manometry because I’m wondering if I might have dyssynergic defecation. Does anyone have this & treated it?

I also recently started osteopathy.

I’ve tried SO many things:

– different probiotics

– supplements to fix deficiencies (vitamins, minerals)

– herbal antibiotics (for SIBO/IMO)

– low FODMAP diet

– low histamine diet

– H. pylori treatment

– Nystatin stada (just in case of fungal overgrowth)

– even the “SIBO yogurt” (L. reuteri)

- hormones / pill for endometriosis

Nothing helped.

At this point it’s affecting my daily life a lot. It’s EVERY single day and I’m exhausted.

Has anyone experienced something similar?

Or has any idea what this could be or what I should look into next? I really don‘t know what to do anymore.

I’d really appreciate any input 🙏❤️