What reaction/deficiency could lead to irritability day after working out?

Sorry, I’m not sure how to phrase this.

I’m homozygous for the C667T variant. I have heterozygous COMT. I have MCAS and PCOS and I’m on birth control, metformin and spironolactone. I’m not medicated for MCAS, I just generally avoid high histamine foods. I’m not currently supplementing with anything because I tend to react poorly to them.

I walk about 10k steps per day but otherwise don’t work out much. Yesterday, I did 50 squats. Literally that’s it haha, and I’m a tiny bit sore today but more notably: I’m irritable for no reason (very unlike me) and having difficulty focusing—like left the fridge open and forgetful.

Over the years of having MCAS I’ve gotten pretty used to odd and subtle shifts but I haven’t noticed something like this before and was wondering if anyone can relate or might know why.

Thanks so much!