Tretinoin and azelaic acid the same night?

Routine Help

Hi, so far I've been using this gel that consists of tretinoin 0.05% and clyndamicin 1% for i think 2 weeks. I use that one night, and azelaic acid 20% the other.

Would it be okay if I applied tretinoin, waited like 15 minutes, and then applied azelaic acid? Do I need to wait more? Please tell me if I do, and tell me how much I should wait. Will this not make the tretinoin less effective?

I am asking this because I have experienced no irritation nor peeling so far and maybe I could get better results if I use it every night (I know it takes time, I am patient, just worrying if I'm doing the right thing). I was also told I could apply azelaic acid in the morning, but I feel like that's not convenient for me because in the morning i only put sunscreen and that's it. If I applied anything under it, I think it would feel even greasier and I'd feel the need to wash it off.

Posted Apr 29, 2026, 7:09 AM UTC

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