Anyone else get joint pain, fatigue, muscle twitches, headaches reacting to food or heat?

This may be something other than my CIRS like MCAS/histamine/mast cell issues or leaky gut but noticed any time I react to a meal I get body/joint pain WITH random muscles twitching… wonder if that’s the histamine/mediators or more of a “leaky gut” thing. It goes away within an hour or so. But the act of eating sometimes will give me face flushing, bowel rumbling, chest tightness, muscles twitching, headache, then systemic flu like symptoms if I’m already in a moderate flare or already primed to react. Seems like everything is revolved around my gut and other than diet would stuff like zinc carnosine, seeking health histaminX probiotic, glutamine, etc help? Thank you.