This Treatment For Ulcerative Colitis Worked For Me

Personal experience

I kept my UC in remission for 11 years by taking Psyllium Seed (Plantago ovata) powder mixed with water 3 times a day. It worked as well as the Pentasa I used for 2 years. When I reached the end of my tolerance for Pentasa, I switched to ground whole Psyllium Seeds. It's the inner part of the seed that's beneficial, not the husks, I sifted them out. Here's just one research paper I found with a Google search.

Randomized clinical trial of Plantago ovata seeds (dietary fiber) as compared with mesalamine in maintaining remission in ulcerative colitis. Spanish Group for the Study of Crohn's Disease and Ulcerative Colitis (GETECCU) - PubMed

Results: Of the 105 patients, 102 were included in the final analysis. After 12 months, treatment failure rate was 40% (14 of 35 patients) in the Plantago ovata seed group, 35% (13 of 37) in the mesalamine group, and 30% (nine of 30) in the Plantago ovata plus mesalamine group. Probability of continued remission was similar (Mantel-Cox test, p = 0.67; intent-to-treat analysis). Therapy effects remained unchanged after adjusting for potential confounding variables with a Cox's proportional hazards survival analysis. Three patients were withdrawn because of the development of adverse events consisting of constipation and/or flatulence (Plantago ovata seed group = 1 and Plantago ovata seed plus mesalamine group = 2). A significant increase in fecal butyrate levels (p = 0.018) was observed after Plantago ovata seed administration.

Conclusions: Plantago ovata seeds (dietary fiber) might be as effective as mesalamine to maintain remission in ulcerative colitis.

Posted May 1, 2026, 9:10 PM UTC

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