Can antidepressants negatively affect personality, as perceived by others?
I know they can help many people, and I'm not dismissing that, but can they also negatively affect personality, as perceived by others around them, for example making a person more unfiltered, uncaring, selfish, etc?
If it's true they can do this, I'm not that interested in the question of whether antidepressants bring out something that was always there and dormant in a personality, or instead whether they change personality in a way that wouldn't occur on its own. It's an interesting question, but either way the end result as it affects others is the same and that's what I'm asking about.
Have any researchers or clinicians with much experience given some top-level comments on this that non-experts can understand?
Posted May 2, 2026, 4:27 AM UTC