Traveling with a guitar?

Hate to sound like an idiot but I know that changes in temperature and humidity are hard on guitars, so how do people travel with them in the truck/car/van without damaging them? I assume every time it gets hot in the day and cold at night it takes some time off the life of the guitar but I was just wondering if I’m overthinking it or if there’s some kind of trick to bringing a guitar with you everywhere without hurting the instrument