Really depressed after stopping. Normal?
Hi all. I recently came off Effexor (~1 month ago). I came off with a Zoloft cross-taper (started it, stopped it, than started it again), which I am still taking at 20mg.
Over the past week or so, my mood has completely plummeted. I feel awful. I have my emotions back, but it's all the negative, and it's hitting me really hard. I just feel so sad and worthless.
I haven't felt this sad since I started Effexor (it just made me numb), but I don't want to say it's 're-emerging depression' when it could be protracted withdrawals.
Has anyone else felt very depressed after coming off Effexor? How did you push through it?
Posted May 6, 2026, 11:29 PM UTC
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