Lumyrz follow up
I posted a couple months back that i just started Lumyrz after being on xyrem for over 10 years. I initially stated that Lumyrz is more effective.
For those that aren't familiar, Lumyrz is a one dose sodium oxidate, and Xyrem requires two doses. Same drug essentially. They help you get quality sleep and greatly reduce cataplexy symptoms (for me at least)
It's now my opinion that they are both very similarly effective. I get the same amount of sleep on both drugs, but I'm taking one g more a night of the Lumyrz than I took w Xyrem. I get the munchies in the middle of the night pretty consistently w Lumyrz, but with Xyrem it was much less often. Funny thing is, sodium oxybate has an appetite suppressing effect for me for most of the day, but the opposite if i wake up in the middle of the night. Those are the two most significant side effects for me. I think I also developed a bit of morning anxiety which is also a known side effect. I didn't have that w xyrem.
Lumyrz tastes much worse imo, but i like the single dose packets rather than mixing two doses w xyrem.
If anyone has any questions about comparing the two drugs specifically, I'll try to respond.
Posted May 10, 2026, 2:15 PM UTC