Using MacBook Pro M5 as an organic chemistry student

I’ve been always using Windows, but have decided to try out MacOS. Softwares that I use mostly, MNova, TopSpin, ChemDraw and MS Office, worked pretty smoothly on Windows. What is the situation with the mentioned software on MacOS? I've seen some people complain about the performance of those softwares (eg pasting a ChemDraw object into MS Word). Has the situation improved in 2026? Why would it be good or not good to buy a MacBook Pro in my situation?