Why do my peps dislike me now? lol

Hi there! I'm not new. Been taking peps for 2 years or so now. I cycle off and on mostly between 5-6 peps. I have noticed lately that I am now getting itchy small welts (that go away in a few hours) when I pinn ANY pep now. I use to NEVER get anyyyy site reaction from $$31. 5AM. NAD. And Mots being the worse (which I had to completely stop and get rid of). The only one I dont get a site reaction is with reta. Anyone ever experience NEVER having site reactions to NOW having them?