Is Rinvoq my last option?

Question

Hello all,

I was diagnosed in March of this year. I started Infliximab at a lower dose than my GI wanted because my insurance would only approve 5mg per infusion instead of 10mg.

Since starting Infliximab I’ve needed a whopping 5 blood transfusions. 2 just in the ER, and now 3 in yet another hospital trip. My GI wants me to do my last loading dose of Infliximab this week, and to see if I get the full effects of the medicine. If not, she wants me to switch to Rinvoq.

I’m concerned, because as I understand it, Rinvoq is a super potent and like a last chance med for people who don’t respond to anything else. So if I fail Infliximab, am I gonna have to get my colon removed?

The other thing is, I’ve had a few CT scans and ultrasounds, and my colon since starting Infliximab has slowly become less inflamed. Now instead of my whole colon it seems like only my ascending colon and rectum are inflamed. So, clearly SOMETHING is working.

I’m just really paranoid about my colon getting removed lol

Posted May 12, 2026, 2:54 PM UTC

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