Depersonalization + many other things - Trazodone?

Hi,
to put long story short: in September I was prescribed venlafaxine + pregabalin & trazodone for sleep. It was a hell for me, especially in the mornings.

Why?

Terrible adrenaline dumps with derealization and depersonalization, feeling naseous, shaky, sweating and like fainting. Every day 7-11 AM.

They replaced venlafaxine with escitalopram. It became manageable but then I got semaglutide for weight loss (took only one dose) and it brought that hell again.

Now, it's been 6 months since my one and only semaglutide dose. Every day I keep having those hellish symptoms, escpecially in the mornings.

I read a little bit about POTS - and thought - maybe trazodone is causing all of that?

I have not fainted so far, maybe because adrenaline dumps keep me awake.

Have you ever heard about trazodone causing all of that? They keep saying that it is my fault, that it is stress related. But I know that it is def not due to my stress (I am calm af).

Posted May 13, 2026, 6:25 PM UTC

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