Switched from Luvox to Lexapro and depression came back. Is this normal?

New to Lex

Hi everyone! I started taking Luvox in October 2025 for anxiety and depression. It worked relatively fast and helped a lot, but it was way too sedating for me. I was literally falling asleep all the time.

My psychiatrist suggested switching to a more activating SSRI, Lexapro. I took my first 10mg dose on April 22nd, then upped to 20mg after about a week. That might have been too fast?

Now my feelings of despair and meaninglessness are back ;( It feels like I’m back where I started before Luvox.

Has anyone else experienced a relapse of depression like this when switching SSRIs? Is this just a normal part of the adjustment period? Should I wait it out for Lexapro to kick in?

Thanks for any advice!

Posted May 13, 2026, 6:26 PM UTC

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