Switched from Luvox to Lexapro and depression came back. Is this normal?
Hi everyone! I started taking Luvox in October 2025 for anxiety and depression. It worked relatively fast and helped a lot, but it was way too sedating for me. I was literally falling asleep all the time.
My psychiatrist suggested switching to a more activating SSRI, Lexapro. I took my first 10mg dose on April 22nd, then upped to 20mg after about a week. That might have been too fast?
Now my feelings of despair and meaninglessness are back ;( It feels like I’m back where I started before Luvox.
Has anyone else experienced a relapse of depression like this when switching SSRIs? Is this just a normal part of the adjustment period? Should I wait it out for Lexapro to kick in?
Thanks for any advice!
Posted May 13, 2026, 6:26 PM UTC
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