New bloodwork day! (Happy Bigender Noises)
It's really uplifting to get that new bloodwork and learn your transition is on track! Last night, my results arrived, and everything about my non-binary HRT regimen is falling into place. I'm taking 50mg daily of bicalutamide with a very extensive, genetically targeted vitamin supplement regimen.
When I started five months ago, my endocrinologist asked me what was going to happen with all the estrone (E1) generated from my regimen. My starting E1 level was 50 and my starting estradiol (E2) level was 36. Six weeks into treatment, my E1 level was 133 and my E2 dipped to 33.
Here we are three months later and my E2 level is up to 45, and my E1 level is down to 59.
This is great news as it shows my body is converting all of that E1 into estradiol!
At the same time my testosterone levels are over 1000 which is enough to keep the masculine features I want around too, despite 60-80% of that being blocked.
What does this mean for me? The feelings of mental clarity that I was so desperately seeking when I arrived here last August are definitely in place.
And I'm definitely noticing the transition affects more today. The top growth I was seeking is happening nicely. And even with those low levels, alongside the androgen blockade, I'm getting the kind of slow steady top growth that I wanted.
Hope everybody else on this sub who is on HRT is getting the results they're looking for. Best wishes to all of y'all!
Posted May 28, 2026, 10:49 AM UTC