Looking for advice on upgrading my PC (GPU + PSU + maybe more)

Hey everyone,

I’m planning to upgrade my PC and wanted to get some opinions before I buy anything so I don’t mess up my build or waste money.

Current specs:

CPU: AMD Ryzen 5 5500

GPU: Radeon RX 6600 (8GB)

RAM: 32GB

Motherboard: ASUS PRIME B450M-A II

PSU: 350W

What I want to upgrade for:

Better performance in games (mostly 1080p, maybe 1440p later)

NVIDIA GPU for CUDA

Planned upgrades so far:

PSU upgrade: 650W

NVIDIA GPU (not sure which one fits best)

Also I do want to upgrade the case purely for the looks of the "new build" (i currently have an old dell case)

I’m definitely open to suggestions and different upgrade paths. I have a micro center near by.