Anyone improved their flatness/anhedonia on Retatrutide?

Hi,

I’m on 2.5mg Retatrutide (third dose) and losing weight steadily, which is great. However, I’m really struggling with feeling emotionally flat / anhedonia (reduced pleasure in things).

I have a history of depression and I’m on escitalopram, plus Elvanse for ADHD. I also just went through a bad breakup, so it’s hard to tell what’s causing what.

Has anyone here been on a similar combo (Retatrutide/GLP-1 + SSRI + stimulant) and experienced this?

• Did the flat feeling get better with time, or did it stay/worsen?
• Did you continue the medication or stop?
• Any tips for managing mood while staying on it (or after stopping)?
• Was the weight maintenance realistic after stopping if you kept training + high protein + steps?

I really want to protect my mental health but I also don’t want to lose the progress I’ve made. Any experiences or advice from people in a similar situation would mean a lot. Thank you.