Favorite peptides for perimenopausal women and why

Please give me your faves and what you experienced on them.

Note: I tested my hormones recently and may be eligible to get HRT but if it’s not necessary on any specific peptides, please share.

Here are some of my experiences:

MOTS-C - got it for energy but notice no difference. Will taking SS-31 really make a difference or is there something better.

Reta - 1mg micro dosing for 3 months. Best results for me from any peptide. Only downside is I am more subdued and less sociable at times but maybe that’s a good thing. I have ADD. I might taper off or dose only every other week since I’ve reached goal weight.

KLOW - thawed out my frozen shoulder in a couple weeks, healed my gut and skin and hair look great. I will always keep this one in the rotation. Love, love, love

NMN - I take this sublingually as a pathway to NAD+ instead of NAD+ subq directly. I started with this before anything else and it makes me more mentally alert but not energetic.

Melanotan 2- I love this one. I only use one small vial a year in the spring/summer. I get the perfect tan that lasts all year with just a few times out in the sun. I do feel more energy on this also. I know this is more cosmetic but I love feeling the sun on my skin and having a sun kissed glow. I don’t stay out long once tan is achieved. Also, I don’t burn so maybe it provides better protection with the added melanin?

Posted Jun 6, 2026, 9:40 PM UTC

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