Help Stomach Burning

Question :snoo_thoughtful:

Has anyone experienced recurring upper stomach burning/tightness on Wegovy?

I’m currently on 0.5 mg and supposed to move up to 0.75 mg next week. I’ve been having on-and-off stomach issues since starting Wegovy, including burning and a tight/gnawing feeling in my upper abdomen along with occasional nausea, burping, cramping, and diarrhea.

The symptoms aren’t constant. I’ll have several days where I feel completely fine, and then I’ll have a flare that lasts a day or two. This has happened about 3–4 times now.

A few things that may be relevant:

I had IBS before starting Wegovy, so it’s hard to tell what’s IBS versus medication side effects.

I’m not vomiting and can keep food and fluids down.

I’ve noticed it can happen after eating, but I haven’t been able to identify one specific trigger food.
Antacids seem to help somewhat.

I’ve lost weight on the medication and would prefer not to stop if possible.

I talked to my doctor last week and she wasn’t overly concerned, but told me to let her know if it continues. I have another appointment scheduled.

For anyone who experienced something similar:

Did it get better with time?
Did you stay at the same dose longer?
Did it turn out to be reflux/gastritis, IBS, or just a normal Wegovy side effect?

Just looking to hear other people’s experiences.

Posted Jun 7, 2026, 4:30 AM UTC

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