Let’s talk about medication
For context, I’ve recently had my diagnosis of persistent depression revised to bipolar 2 and borderpolar is within the realm of possibility. I’ve been on most medications, but I’m particularly incompatible with SSRIs/SNRIs due to reasons I won’t get into, mainly just adverse effects. I’ve been on Effexor, Prozac, Lexapro, and probably Zoloft as well (I’ve lost count lol). None of which worked for aforementioned reasons. Then we try antipsychotics. Lurasidone, risperidone, Abilify, Seroquel, and caplyta. Of which, Seroquel was the only to give me any sort of benefits in terms of anxiety when taken in conjunction with Abilify. Unfortunately, all of them caused me to have worsening SI. It wasn’t until I was prescribed lamotrigine that I saw any improvement with my mood symptoms, that was until I developed the early symptoms of SJS (sore throat, blistery hives, fever, etc.).
Due to insurance reasons, I’ve swapped healthcare providers, got referred to a specialist because of how treatment resistant my condition is and I’ve been looking into other options for medication, studying clinical trials for which combinations have greater efficacy. Particularly, I’ve been seeing stuff about lithium and zyprexa having good results for the symptoms I have. Have those two worked well for anyone? Has anyone even experienced similar issues? Can anyone here attest to the efficacy of their medications if they’ve had similar issues? What worked for y’all?
Posted Jun 8, 2026, 4:58 AM UTC