My 4i4 keep muting itself

Help! I've practically done everything possible. My Scarlett 4i4 (3rd Gen) randomly mutes itself. It doesn't disconnect; it just becomes muted. It happens for no particular reason — for example when I use AmpliTube or when I play Minecraft. I tried optimizing CPU cores with Process Lasso, tried multiple drivers, and tried every combination of buffer sizes and sample rates, but nothing changed. I noticed, however, that when it mutes the input still flows into the PC (for example AmpliTube's VU meters keep working), yet my interface does not produce any sound until I change the sample rate in Focusrite Control. It is very annoying and is making the audio interface practically useless.

Does someone of you ever encountered this problem? How did you manage to solve it?

Thank you guys.

Posted Jun 10, 2026, 4:34 PM UTC

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