Has anyone switched from a 6-MP to a biologic and maintained clinical remission during the change?

Question

I have been in clinical remission for over 8 years now, thanks to 6-MP. Only problem is that when I get sick, I get sick HARD. The flu will completely knock me off my feet for a few days atleast where I can’t even function.

Due to 6-MP, almost all my blood levels are slightly below normal. I understand that 6-MPs “nuke” your immune system and that biologics are more “targeted” and less impactful on the immune system.

Is it worth exploring the possibility of getting off the 6-MP and switching to biologic? I’ve been in clinical remission for so long maybe I’m just taking it for granted and should suck it up. I don’t know, but now that my toddler is in daycare I am getting sick almost every month or two.

Posted Jun 11, 2026, 9:31 PM UTC

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