Why does berberine make my liver hurt?

I don't even take a lot, only about 50 mg a day. Yet whenever I take it my liver starts hurting afterward. I thought berberine is supposed to be good for the liver?

I'd quit taking it but I have a sugar addiction and berberine really helps to control the glucose spikes I would otherwise get. I now take 200 mg milk thistle with every 50 mg of berberine and it's helped with the liver pain a bit but not completely.

Does berberine make anyone else's liver hurt or is it just me? And what could be the reason?