Will my anxiety ever feel easier?

After years of struggling to manage anxiety and depression, I still feel that nothing has substantially helped my anxiety. Anxious thoughts, sure, but the worst of it being restless and uncomfortable in my body. Feeling like I am exposed walking through the world and constantly having big reactions to small things. Therapy has given me some tools. Meds haven’t really helped my anxiety yet. I have some coping skills that get me through it, because ultimately I’m able to leave my house and do things I need to do. But I feel like I’m constantly treading water to keep my head up, even with adjustments to my life. I don’t know how I can financially/realistically reduce my demands any more 😞 My spouse has a disability as well. Has anyone had luck with managing anxiety that feels like you’re so sensitive to everything?