Anyone with mild Crohn’s / ileal Crohn’s on Entyvio? Looking for experiences

Hey everyone,

My GI is recommending Entyvio because he feels my Crohn’s is on the milder side, and I’m trying to figure out if it makes sense for my case. HE also says it has one of the best safaty profiles but its milder and takes longer to work.

My Crohn’s seems mostly localized to the terminal ileum (and a little cecum colitis involvement).

My recent findings:

  • IUS (April 2026): active ileitis, bowel wall thickening (4.1mm) over 5.4cm, mild-moderate Doppler flow
  • Colonoscopy (May 2026): mild active nonspecific ileitis in terminal ileum
  • Mild nonspecific colitis in cecum with aphthoid lesion
  • Rest of colon looked normal
  • No strictures, fistulas, or major complications
  • MRI has been mostly normal/no major progression

My symptoms:

  • Sharp pains in lower abdomen
  • sever bloating
  • Fatigue
  • Joint pain when I flare
  • Constipation dominant but when diarrhea the pain is immense. (as if theres not much space to past by in the area)
  • General feeling of inflammation even when testing looks “mild”
  • Not to mention iron levels and vitamin D levels usually low

I’ve done Budesonide a few times and it helps, but symptoms always return. I’m still on Mesalamine, doctor taking me off, says it wont do much for me..

Im trying to see if indeed his recommendation would be the best all around drug for my symptoms and also better then the others that are out there.

Looking forward to talking with you all

Thanks.

Posted Jun 12, 2026, 11:41 PM UTC

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