Can guanfacine cause heightened aggression?
My kiddo for the first few weeks or month or so seemed to do okay on it. Better at home but still struggled in school. As of lately school has been AWFUL and way worse than ever before. Home is still okay. He’s snapping excessively over small things (he used to before, but now it’s literally a daily occurrence, multiple times per day). Hes on biphentin 20mg in the morning and guanfacine 2mg at night, and is 7 years old. He frequently says he’s sick of his “stupid dumb behaviour” and it breaks my heart. It’s getting to the point where he missed out on a game and fell to the floor and started hitting himself. I don’t know what to do. Has anyone seen these kinds of things get worse after starting this med? We accidentally forgot a dose one day and his teacher noted he was much more hyper, but anxiety was reduced and there were no outbursts that day. I know one day is very small and I could have been coincidence, but it has me wondering.
Thanks
Posted Jun 12, 2026, 11:50 PM UTC