[ISM] Any tips as to not feel like trash the first 8 hours of the day?

Professionally diagnosed with indolent systemic mastocytosis since about a year (after a couple more of trying to understand what's been happening to me), I'm taking cetirizine, famotidine and montalukast and tons of complements but I still always feel horrible upon waking up and take about 8 hours to finally feel a bit capable. Have you been dealing with this too? What's been working for you to get your life back?

My days are usually waking up, taking an hour to emerge from "coma", taking meds, sitting in front of computer a couple of hours but incapable of doing anything, going back to bed, sleeping for another 1-3 hours, then maybe after a couple of hours, I'll start to feel "ok" again. Not great, but I can pay bills, respond to e-mails, etc. and I'm tired of it, tired of seeing my career, plans, social life, etc. going down the drain.