I have been suffering from a gastric ulcer for the past nine months.

Drugs/Treatments

I have been suffering from a gastric ulcer for the past nine months. I regularly consult gastroenterologists. Over the last six months, I have seen four gastroenterologists. After evaluating my condition, all of them prescribed Dexlansoprazole 30 mg (1+0+1) along with other medications.

A few days ago, I visited another gastroenterologist and again explained my symptoms, including the fact that I had been taking Dexlansoprazole continuously for six months. He then changed my medication to Pantoprazole 20 mg twice daily for six weeks and advised me that taking acid-suppressing medication continuously for such a long time is not always ideal and that sometimes a one-week break may be appropriate.

Following his advice, I stopped taking Dexlansoprazole and decided to wait one week before starting Pantoprazole. However, on the very first day after stopping Dexlansoprazole, my stomach acid seemed to increase very rapidly, even though I had not eaten any foods that would normally trigger acid production. As a result, I was forced to start taking Pantoprazole according to the prescription.

My questions are:

What could be the reason for such a rapid increase in stomach acid immediately after stopping Dexlansoprazole?

If I stop taking Pantoprazole now, will my stomach again produce acid very rapidly and in greater amounts than a normal person’s stomach?

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Posted Jun 13, 2026, 11:44 PM UTC

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